Study of 3D-printed chitosan scaffold features after different post-printing gelation processes

Bergonzi, C and Di Natale, A and Zimetti, F and Marchi, C and Bianchera, A and Bernini, F and Silvestri, Marco and Bettini, R and Elviri, L (2019) Study of 3D-printed chitosan scaffold features after different post-printing gelation processes. Scientific Reports, 9 (362). ISSN 2045-2322

Text 10.1038@s41598-018-36613-8.pdf Download (1MB)

Abstract

3D biomaterial manufacturing strategies show an extraordinary driving force for the development of innovative therapies in the tissue engineering field. Here, the behaviour of 3D printed chitosan (CH)-based scaffolds was explored as a function of the post-printing gelation process. To this purpose, gel forming properties of different media were tested on their capability to retain 3D structure, water content, mechanical resistance and surface/internal porosity. Three different gelation media (i.e. KOH 1.5 M, Na2CO3 1.5 M, ammonia vapours) were selected and the 3D CH scaffolds were tested in terms of biocompatibility toward fibroblast as skin associated human cell line.

Item Type:	Scientific journal article, Newspaper article or Magazine article
Subjects:	Engineering > Production & manufacturing engineering > Manufacturing systems engineering > Production processes
Department/unit:	Dipartimento tecnologie innovative > Istituto sistemi e tecnologie per la produzione sostenibile
Depositing User:	Marco Silvestri
Date Deposited:	08 Jan 2020 07:43
Last Modified:	08 Jan 2020 07:43
URI:	http://repository.supsi.ch/id/eprint/11406

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