Protein--dendron conjugates for DNA binding: understanding the effect of the protein core on multivalency

Pavan, Giovanni Maria and Kostiainen, Mauri A and Danani, Andrea (2011) Protein--dendron conjugates for DNA binding: understanding the effect of the protein core on multivalency. RSC Advances, 1 (9). pp. 1677-1681. ISSN 2046-2069

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Abstract

In this work we have used molecular dynamics simulations to explore the binding between two different protein–dendron conjugates and double stranded DNA. Different protein cores protect the binding site from the external environment, but can also influence the multivalent recognition between the spermine ligands of the dendron and the DNA.

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