Magli, Cristina and Corani, Giorgio and Giusti, Alessandro and Castelletti, Eleonora and Gambardella, Luca Maria and Gianaroli, Luca (2012) A prognostic model for multiple-embryo transfers. Human Reproduction, 27 (2). pp. 162-205. ISSN 1460-2350
Full text not available from this repository.Abstract
The EU prognostic model is composed by two sub-models: the E sub-model estimates the probability of an embryo being viable; the U sub-model estimates the probability of the woman to sustain a viable embryo (maternal receptivity). The establishment of pregnancy requires one or more viable embryos and a receptive maternal environment. There is however no general consensus on which variable to included in the E and U sub-models. On a related topic, defining a strong predictor of embryo viability is still an open problem. Morphological criteria are used to identify top-quality embryos; some studies suggest that better predictivity can be achieved combining into a single score the grades obtained by the embryo in different stages. We thus scored the embryos as non-top, top and top-history, the latter score being assigned to embryos judged of top quality in several observations. In this study we analyzed 352 IVF cycles (average patients age: 36 years; average number of transferred embryos: 2; clinical pregnancy rate: 21.5%) through the EU model, adopting a statistical criterion to choose the variables in the E and U sub-model, assessed the viabilities of non-top, top and top-history embryos and measured the predictive ability of the model.
Item Type: | Scientific journal article, Newspaper article or Magazine article |
---|---|
Additional Information: | Supplement: Abstract book, Proc. Annual Meeting ESHRE 2012 |
Subjects: | Mathematical sciences > Statistics > Applied statistics > Medical statistics |
Department/unit: | Dipartimento tecnologie innovative > Istituto Dalle Molle di studi sull’intelligenza artificiale USI-SUPSI |
Depositing User: | Giorgio Corani |
Date Deposited: | 10 Jun 2014 05:42 |
Last Modified: | 06 Jun 2016 06:45 |
URI: | http://repository.supsi.ch/id/eprint/4722 |
Actions (login required)
View Item |