Distribution and quantification of antibiotic resistance genes in a large subalpine lake (Lugano Lake) and tributary rivers

Mauri, Federica and Pianta, Elisa (2023) Distribution and quantification of antibiotic resistance genes in a large subalpine lake (Lugano Lake) and tributary rivers. Journal of Global Antimicrobial Resistance, 33. pp. 249-255. ISSN 22137165

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Abstract

Antibiotic resistance genes (ARGs) are causing increasing problems, especially in clinical settings. Nowadays, they are considered important environmental contaminants, but little is known about their fate in the environment or how they affect natural microbial populations. In the environment, especially in water affected by anthropic activities such as discharge of hospital, urban, and industrial wastewater treatment plant (WWTP) and agricultural runoff, antibiotic determinants may become part of the environmental gene pool, spread horizontally, and be ingested by humans and animals via contaminated food and drinking water. The aim of this work was to monitor long-term the presence of antibiotic resistance determinants in water samples collected from a subalpine lake and some tributary rivers located in the southern part of Switzerland, and to assess if anthropic activities could influence the distribution of antibiotic resistance genes present in water environments.

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