Differences in intention to inform relatives and rates of cascade testing in families concerned with hereditary breast and ovarian cancer and Lynch syndrome: The Swiss CASCADE cohort

Sarki, M and Ming, C and Aissaoui, S and Burki, N and Caiata Zufferey, Maria and Erlanger, T and Graffeo-Galbiati, R and Heinimann, K and Heinzelmann-Schwarz, V and Monnerat, C and Probst-Hensch, N and Rabaglio, M and Zürrer, U and Chappuis, P and Katapodi, M (2022) Differences in intention to inform relatives and rates of cascade testing in families concerned with hereditary breast and ovarian cancer and Lynch syndrome: The Swiss CASCADE cohort. In: European Human Genetics Conference, 11-14.6.2022, Wien.

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Abstract

The study examined theory-based predictors of index cases’ intention to invite relatives to a family-based cohort, rates of cascade testing among relatives, and preferences of those who carry a pathogenic variant for patient- or provider-mediated communication of testing results to untested relatives.

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