Abizari, Abdul-Razak and Moretti, Diego and Schuth, Stephan and Zimmermann, Michael Bruce and Armar-Klemesu, Margaret and Brouwer, Inge D. (2012) Phytic Acid-to-Iron Molar Ratio Rather than Polyphenol Concentration Determines Iron Bioavailability in Whole-Cowpea Meal among Young Women. JOURNAL OF NUTRITION, 142 (11). pp. 1950-1955.
Full text not available from this repository.Abstract
Limited data exist on iron absorption from NaFeEDTA and FeSO4 in legume-based flours. The current study compared iron absorption from NaFeEDTA and FeSO4 as fortificants within and between red and white varieties of cowpea with different concentrations of polyphenols (PP) but similar phytic acid (PA)-to-iron molar ratios. We performed a paired crossover study in young women (n = 16). Red-cowpea (high-PP) and white-cowpea (low-PP) test meals (Tubani) were each fortified with (Fe-57)-labeled NaFeEDTA or (Fe-58)labeled FeSO4 and were randomly administered. Iron absorption was measured as erythrocyte incorporation of stable iron isotopes. Per serving, the mean (+/-SD) PP concentrations of the white- and red-cowpea based meals were 74 +/- 3.6 and 158 +/- 1.8 mg, respectively, and the molar ratio of PA to iron was 3.0 and 3.3. Iron bioavailabilities from red and white cowpeas were 1.4 and 1.7%, respectively, in NaFeEDTA-fortified meals and 0.89 and 1.2%, respectively, in FeSO4-fortified meals. Compared with FeSO4, fortification with NaFeEDTA increased the amount of iron absorbed from either of the cowpea meals by 0.05 to 0.08 mg (P < 0.05). Irrespective of the fortificant used, there was no significant difference in the amount of iron absorbed from the 2 varieties of cowpea. The results suggest that NaFeEDTA is more bioavailable in legume-based flours compared with FeSO4. In cowpea-based flours, the major determinant of low iron absorption may be the high molar ratio of PA to iron and not variations in PP concentration. J. Nutr. 142: 1950-1955, 2012.
| Item Type: | Scientific journal article, Newspaper article or Magazine article |
|---|---|
| Subjects: | Subjects Allied to Medicine > Nutrition > Dietetics Subjects Allied to Medicine > Nutrition > Nutrition not elsewhere classified |
| Department/unit: | Fernfachhochschule Schweiz |
| Depositing User: | Diego Moretti |
| Date Deposited: | 24 Sep 2019 05:11 |
| Last Modified: | 24 Sep 2019 05:11 |
| URI: | http://repository.supsi.ch/id/eprint/10824 |
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